JC-1

CHF 293.00
In stock
CDX-T0046-M01010 mgCHF 293.00
CDX-T0046-M100100 mgCHF 1'531.00
More Information
Product Details
Synonyms JC-1 jodide
Product Type Chemical
Properties
Formula C25H27Cl4IN4
MW 652.23
CAS 3520-43-2
Source/Host Chemicals Synthetic.
Purity Chemicals ≥90% (HPLC)
Appearance Dark violet solid.
Solubility Soluble in methanol, DMSO.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key FYNNIUVBDKICAX-UHFFFAOYSA-M
Smiles [I-].CCN1C(=C\C=C\C2=[N+](CC)C3=C(C=C(Cl)C(Cl)=C3)N2CC)N(CC)C2=C1C=C(Cl)C(Cl)=C2
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF

A dual-emission potential-sensitive probe that can be used to measure mitochondrial membrane potential. JC-1 is a green-fluorescent monomer at low membrane potential. At higher potentials, JC-1 forms red-fluorescent "J-aggregates," which exhibit broad excitation and very narrow emission spectra. The ratio of red to green fluorescence of JC-1 is dependent only on membrane potential, and not influenced by mitochondrial size, shape, or density.

Product References

(1) G.Y. Guralchuk et al.; J. Phys. Chem. C 112(38), 14762 (2008) | (2) S.T. Smiley et al.; PNAS 88, 3671 (1991) | (3) M. Reers, et al.; Biochem. 30, 4480 (1991)

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