Pseurotin D

CHF 135.00
In stock
BVT-0426-M0011 mgCHF 135.00
BVT-0426-M0055 mgCHF 395.00
More Information
Product Details
Product Type Chemical
Properties
Formula

C22H25NO8

MW 431.4
CAS 77409-68-8
Source/Host Chemicals Isolated from Aspergillus fumigatus.
Purity Chemicals ≥98% (HPLC, NMR)
Appearance Off-white to beige solid.
Solubility Soluble in DMSO, chloroform or dichloromethane.
Identity Determined by 1H-NMR.
Declaration Manufactured by BioViotica.
InChi Key GZAYJWNDYQINEI-OLSIJDASSA-N
Smiles CC1=C([C@@H](O)/C=C/C(O)CC)O[C@@]2([C@@H](O)[C@](OC)(C(C3=CC=CC=C3)=O)NC2=O)C1=O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Store solutions at -20°C in the dark.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
  • Isomeric to pseurotin A (Prod. No. BVT-0003).
  • Anticancer and antiparasitic compound.
  • Apomorphine antagonist. Neuroleptic agent.
  • Inhibitor of IgE production.
Product References
  1. Pseurotin B, C, D and E. Further new metabolites of Pseudeurotium ovalis STOLK: W. Breitenstein et al.; Helv. Chim. Acta 64, 379 (1981)
  2. Biologically active pseurotins A and D, new metabolites from Aspergillus fumigates, process for their preparation and their use as apomorphine antagonist: J. Wink, et al.; Eur. Pat. Appl. EP546475A1 (1993)
  3. Pseurotin A and its analogues as inhibitors of immunoglobulin E production: M. Ishikawa, et al.; Bioorg. Med. Chem. Lett. 19, 1457 (2009)
  4. Antitumor compositions containing pseurotin D: D. G. Kim, et al.; Repub. Korean Kongkae aeho Kongbo KR20110087395 (2011)
  5. Antiparasitic and anticancer constituents of the endophytic fungus Aspergillus sp. strain F1544: S. Martinez-Luis, et al.; Nat. Prod. Comm. 7, 165 (2012)
  6. Elucidation of Pseurotin Biosynthetic Pathway Points to Trans-Acting C-Methyltransferase: Generation of Chemical Diversity: Y. Tsunematsu, et al.; Angew. Chem. Int. Ed. 53, 8475 (2014)
  7. Angiogenesis Inhibitors and Anti-Inflammatory Agents from Phoma sp. NTOU4195: M.-S. Lee, et al.; J. Nat. Prod. 79, 2983 (2016)
  8. Treatment of epilepsy using pseurotins and azaspirofurans: D. Copmans, et al.; PCT Int. Appl., WO 2019043019 A1 20190307 (2019)
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