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Cayman
STING Agonist C11
100
CHF
CHF 100.00
In stock
CAY-27886-500500 µgCHF 100.00
CAY-27886-11 mgCHF 160.00
CAY-27886-55 mgCHF 752.00
CAY-27886-1010 mgCHF 1'101.00
| Product Details | |
|---|---|
| Product Type | Chemical |
| Properties | |
| Formula | C19H18N4O3S |
| MW | 382.4 |
| CAS | 875863-22-2 |
| Purity Chemicals | ≥95% |
| Appearance | A crystalline solid |
| Declaration | Manufactured by Cayman Chemicals. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | KQKWXSQTTDLZSO-UHFFFAOYSA-N |
| Smiles | O=C(NC(NC)=O)C(SC1=NN=C(C2=CC=C(C)C=C2)O1)C3=CC=CC=C3 |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
An agonist of the STING pathway; induces secretion of type I IFN from THF and MM6 cells at 50 µM; induces phosphorylation of IRF3 and increases expression of IFIT1 and viperin in THF cells in a STING-dependent manner; reduces viral titers of chikungunya, Venezuelan equine encephalitis, o'nyong-nyong, Mayaro, and Ross River viruses grown in THF cells (EC90s = 16.44, 16.7, 18.84, 25.19, and 22.57 µM, respectively), an effect that is dependent on the presence of STING and IFNAR.