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Cayman
SR 717 (lithium salt)
94
CHF
CHF 94.00
In stock
CAY-31759-55 mgCHF 94.00
CAY-31759-1010 mgCHF 165.00
CAY-31759-2525 mgCHF 360.00
CAY-31759-5050 mgCHF 541.00
| Product Details | |
|---|---|
| Product Type | Chemical |
| Properties | |
| Formula | C15H8F2N5O3 . Li |
| MW | 351.2 |
| CAS | 2375421-09-1 |
| Purity Chemicals | ≥98% |
| Appearance | A solid |
| Declaration | Manufactured by Cayman Chemicals. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | ODSAJRWPLSVEHJ-UHFFFAOYSA-M |
| Smiles | O=C([O-])C1=CC(F)=C(F)C=C1NC(C2=NN=C(N3C=CN=C3)C=C2)=O.[Li+] |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
A STING agonist (EC50 = 2.1 µM in a reporter assay); selective for STING over a panel of 468 kinases; increases plasma IFN-β and IL-6 levels in mice at 30 mg/kg; increases the intratumor frequency of CD69+CD8+ T cells, reduces tumor growth, and increases survival in a B16/F10 murine melanoma model.