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Cayman
YSK05
131
CHF
CHF 131.00
In stock
CAY-35786-55 mgCHF 131.00
CAY-35786-1010 mgCHF 197.00
CAY-35786-2525 mgCHF 425.00
| Product Details | |
|---|---|
| Product Type | Chemical |
| Properties | |
| Formula | C42H77NO2 |
| MW | 628.1 |
| CAS | 1318793-78-0 |
| Purity Chemicals | ≥90% |
| Appearance | A solution in ethanol |
| Declaration | Manufactured by Cayman Chemicals. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | KURBRAZBXURPCJ-QYCRHRGJSA-N |
| Smiles | CCCCC/C=C\C/C=C\CCCCCCCCOC1(CCN(CC1)C)OCCCCCCCC/C=C\C/C=C\CCCCC |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
An ionizable amino lipid (apparent pKa = ~6.5); has been used in combination with other lipids in the formation of liposomes and LNPs; administration of cyclic di-GMP in YSK05-containing liposomes increases serum levels of IFN-β, IFN-γ, IL-6, and TNF-α and activates NK cells in mice, as well as decreases lung metastasis in a B16/F10 murine melanoma model of metastasis; intravenous administration of factor VII siRNA in YSK05-containing LNPs reduces factor VII activity in isolated mouse plasma.