AdipoGen Life Sciences

White Line Inducing Principle

CHF 160.00
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AG-CN2-0069-M0011 mgCHF 160.00
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Product Details
Synonyms WLIP
Product Type Chemical
Properties
Formula

C54H95N9O16

MW 1126.4
CAS 135096-89-8
Source/Host Chemicals Isolated from Pseudomonas sp.
Purity Chemicals ≥98%
Appearance White solid.
Solubility Soluble in DMSO, ethanol or methanol.
Identity Determined by 1H-NMR and MS.
InChi Key QYEWAEAWMXRMHB-WRNJRVSGBN
Smiles CCCCCCCC(O)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H]1[C@@H](C)OC(=O)[C@@H](NC(=O)[C@@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CO)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](NC1=O)C(C)C)C(C)CC
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Protect from light.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description
  • Lipodepsipeptide (LDP) [1].
  • Used as a diagnostic tool to identify tolaasin-producing bacteria pathogenic to mushrooms and responsible for brown blotch disease [1, 5].
  • Has haemolytic activity. Permeabilizes lipid vesicles and is involved in mushroom tissue alterations by forming transmembrane pores [2].
  • Antimicrobial. Antibacterial. Antifungal [2 - 4].
Product References
  1. Structure of the white-line-inducing principle isolated from Pseudomonas reactans: F. Han, et al.; Acta Cryst. C 48, 1965 (1992)
  2. WLIP and tolaasin I, lipodepsipeptides from Pseudomonas reactans and Pseudomonas tolaasii, permeabilise model membranes: M. Coraiola, et al.; Biochim. Biophys. Acta 1758, 1713 (2006)
  3. Biological characterization of white line-inducing principle (WLIP) produced by Pseudomonas reactans NCPPB1311: P. Lo Cantore, et al.; Mol. Plant Microbe Interact. 19, 1113 (2006)
  4. Bioactive and structural metabolites of pseudomonas and burkholderia species causal agents of cultivated mushrooms diseases: A. Andolfi, et al.; Perspect. Medicin. Chem. 2, 81 (2008)
  5. Genetic and functional characterization of cyclic lipopeptide white-line-inducing principle (WLIP) production by rice rhizosphere isolate Pseudomonas putida RW10S2: H. Rokni-Zadeh, et al.; Appl. Environ. Microbiol. 78, 4826 (2012)
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