anti-IL-17A (human), mAb (17-142F) (FITC)
350 CHF CHF 350.00
AG-20A-0071F-C05050 µgCHF 350.00
FACS: Human PBMCs were cultured with recombinant IL-1β, TGF-β, and IL-6 for 4 days. Cells were then reactivated with PMA/Ionomycin in the presence of monensin for 5h. Cells were stained with anti-IL-17A (human), mAb (17-142F) (FITC) (Prod. No. AG-20A-0071F) and PE anti-CD4. Cells in the lymphocyte gate were used for analysis. Quadrant lines demarcate isotype control.
|Synonyms||Interleukin-17A; CTLA-8; Cytotoxic T Lymphocyte-associated Antigen 8|
|Product Type||Monoclonal Antibody|
|Immunogen/Antigen||Recombinant human IL-17A.|
Flow Cytometry: (1:20-1:500)
Optimal conditions must be determined individually for each application.
|Specificity||Recognizes human IL-17A.|
|Purity Detail||Protein G-affinity purified.|
|Formulation||Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.|
|Shipping and Handling|
|Short Term Storage||+4°C|
|Long Term Storage||-20°C|
After opening, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
|Use/Stability||Stable for at least 1 year after receipt when stored at -20°C.|
|Product Specification Sheet|
IL-17A exhibits multiple biological activities on a variety of cells including the induction of IL-6 and IL-8 production in fibroblsts, the enhancement of surface expression of ICAM-1 in fibroblast, activation of NF-κB and costimulation of T cell proliferation. Induces stromal cells to produce proinflammatory and hematopoietic cytokines.