AdipoGen Life Sciences

Ingenol-5,20-acetonide

CHF 120.00
In stock
AG-CN2-0029-M0011 mgCHF 120.00
AG-CN2-0029-M0055 mgCHF 480.00
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Product Details
Product Type Chemical
Properties
Formula

C23H32O5

MW 388.5
CAS 77573-43-4
Source/Host Chemicals Semisynthetic.
Purity Chemicals ≥95% (HPLC)
Appearance White solid.
Solubility Soluble in methanol, DMSO or dichloromethane.
InChi Key ONMDPPVVEFWDOD-DVBBJZJXSA-N
Smiles [H][C@@]12[C@@H](C[C@@H](C)[C@]34C=C(C)[C@H](O)[C@@]3(O)[C@@H]3OC(C)(C)OCC3=C[C@]1([H])C4=O)C2(C)C
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description
  • Intermediate and starting material for the synthesis and preparation of ingenol 3-ester derivatives.
  • For use in chemical synthesis see references.
  • Has improved shelf life compared to ingenol.
Product References
  1. The chemistry of ingenol. 1. Ingenol and some of its derivatives: J.H. Opferkuch, et al.; Z. Naturforsch. 36b, 878 (1981)
  2. Synthesis of Modified Ingenol Esters: G. Appendino, et al.; Eur. J. Org. Chem. 1999, 3413 (1999)
  3. Ingenol esters induce apoptosis in Jurkat cells through an AP-1 and NF-kappaB independent pathway: M. Blanco-Molina, et al.; Chem. Biol. 8, 767 (2001)
  4. Synthesis of sapintoxin D and N-methylanthranilate-based fluorescent bioprobes: F. Mainieri, et al.; Nat. Prod. Commun. 2, 375 (2007)
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