60 CHF CHF 60.00
AG-CN2-0486-M0011 mgCHF 60.00
AG-CN2-0486-M0055 mgCHF 180.00
AG-CN2-0486-M02525 mgCHF 630.00
|Synonyms||(+)-Epicatechin-(4β-8,2β-O-7)-epicatechin; PCA2; Proanthocyanidin A2; PA2; Procyanidol A2; Procyanidin dimer A2|
|Source/Host Chemicals||Isolated from grape seeds (Vitis vinifera L).|
|Purity Chemicals||≥95% (NMR)|
|Appearance||Pale pink solid.|
|Solubility||Soluble in DMSO, 100% ethanol or methanol. Sparingly soluble in water (0.1 mg/ml).|
|Identity||Determined by 1H-NMR.|
|Shipping and Handling|
|Short Term Storage||+4°C|
|Long Term Storage||-20°C|
Keep cool and dry.
Protect from light.
Protect from moisture and oxygen.
|Use/Stability||Stable for at least 2 years after receipt when stored at -20°C.|
|Product Specification Sheet|
- A-Type proanthocyanidine.
- Potent antioxidant. Free radical scavenger and lipid peroxidation inhibitor.
- Potent low-density lipoprotein (LDL) oxidation inhibitor.
- Antidiabetic. Prevents islet cell apoptosis, hyperglycemia and type 2 diabetes through it's antioxidant properties.
- Antibacterial agent.
- Antiviral. Shown to inhibit viral replication of canine distemper virus (CDV).
- Glycosyltransferase B (GTFB) inhibitor.
- Phenolic constituents in the fruits of Cinnamomum zeylanicum and their antioxidant activity: G.K. Jayaprakasha, et al.; J. Agric. Food Chem. 54, 1672 (2006)
- Influence of cranberry phenolics on glucan synthesis by glucosyltransferases and Streptococcus mutans acidogenicity: S. Gregoire, et al.; J. Appl. Microbiol. 103, 1960 (2007)
- Influence of cranberry proanthocyanidins on formation of biofilms by Streptococcus mutans on saliva-coated apatitic surface and on dental caries development in vivo: H. Koo, et al.; Caries Res. 44, 116 (2010)
- Doubly linked, A-type proanthocyanidin trimer and other constituents of Ixora coccinea leaves and their antioxidant and antibacterial properties: T.O. Idowu, et al.; Phytochemistry 71, 2092 (2010)
- Inhibition of viral RNA synthesis in canine distemper virus infection by proanthocyanidin A2: L. Gallina, et al.; Antiviral Res. 92, 447 (2011)
- Flavonoids from Lindera glauca blume as low-density lipoprotein oxidation inhibitors: G.W. Huh, et al.; Nat. Prod. Res. 28, 831 (2014)
- Procyanidins from the stem wood of Machilus japonica and their inhibitory effect on LDL oxidation: H.J. Park, et al.; Arch. Pharm. Res. 37, 1403 (2014)
- Chemical composition, antioxidant and antinociceptive properties of Litchi chinensis leaves: R.C. Castellain, et al.; J. Pharm. Pharmacol. 66, 1796 (2014)
- Preventive effects of procyanidin A2 on glucose homeostasis, pancreatic and duodenal homebox 1, and glucose transporter 2 gene expression disturbance induced by bisphenol A in male mice: A. Ahangarpour, et al.; J. Physiol. Pharmacol. 67, 243 (2016)