BRS-3 Agonist

CHF 190.00
In stock
AG-CR1-3607-C500500 µgCHF 190.00
More Information
Product Details
Synonyms Bombesin Receptor Subtype-3 Agonist; Compound 5 {10,3}; (2E)-N-[2-(3,4-Dimethoxyphenyl)ethyl]-3-(2-furanyl)-2-propenamide
Product Type Chemical
Properties
Formula

C17H19NO4

MW 301.3
CAS 1426294-15-6
Purity Chemicals ≥97% (NMR)
Appearance White solid.
Solubility Soluble in DMSO or MeOH. Insoluble in water.
Identity Determined by 1H-NMR.
Other Product Data

Bombesin receptor subtype-3 (BRS-3) is known as an orphan G-protein coupled receptor and belongs to the bombesin receptor family. BRS-3 receptor is expressed not only in brain but also in other peripheral organs such as intestine, liver, lung, testes and pancreas. Since BRS-3 deficient mice develop obesity and impaired glycemic regulation, ligands that modulate BRS-3 signaling are potential targets for diabetes and obesity treatments.

InChi Key RTMCVKRRGDEHTR-VURMDHGXSA-N
Smiles COC1=C(OC)C=C(CCNC(=O)\C=C\C2=CC=CO2)C=C1
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
  • Bombesin receptor subtype-3 (BRS-3) agonist.
  • Energy homeostasis regulator.
Product References
  1. Column chromatography-free solution-phase synthesis of a natural piper-amide-like compound library: S. Kim, et al.; ACS Comb. Sci. 15, 208 (2013)
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