AdipoGen Life Sciences


CHF 140.00
In stock
AG-MR-C0002-M0055 mgCHF 140.00
AG-MR-C0002-M02525 mgCHF 560.00
More Information
Product Details
Synonyms 6-Benzylamino-2-(S)-[(1-ethyl)-2-hydroxyethylamino]-9-isopropylpurine
Product Type Chemical


MW 354.5
CAS 186692-45-5
Purity Chemicals ≥99% (NMR)
Appearance White to off-white solid.
Solubility Soluble in DMSO, ethanol or methanol.
Reconstitution Stock solutions can be made up to 10mM in DMSO.
Identity Determined by 1H-NMR.
Smiles CC[C@@H](CO)NC1=NC2=C(N=CN2C(C)C)C(NCC2=CC=CC=C2)=N1
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice After standard reconstitution, prepare aliquots and store at -20°C.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
  • (S)-enantiomer of (R)-roscovitine (Prod. No. MR-C0001).
  • Potent selective cyclin-dependent kinase 1 (CDK1) inhibitor.
  • Potential neuroprotectant for stroke. Crosses the blood brain barrier. Inhibits CDK5, consequently blocking hypoxia-induced apoptosis in neurons.
  • Potential anti-inflammatory compound.
  • Potential antidiabetic compound.
Product References
  1. Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5: L. Meijer, et al.; Eur. J. Biochem. 243, 527 (1997)
  2. Maintenance of meiotic arrest in bovine oocytes using the S-enantiomer of roscovitine: effects on maturation, fertilization and subsequent embryo development in vitro: P. Coy, et al.; Reprod. 129, 19 (2005)
  3. Delayed treatment with systemic (S)-roscovitine provides neuroprotection and inhibits in vivo CDK5 activity increase in animal stroke models: B. Menn, et al.; PLoS One 5, e12117 (2010)
© 2017 Adipogen Life Sciences. Pictures: © 2012 Martin Oeggerli. All Rights Reserved.