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Ancell
anti-DR3 (human), mAb (ANC2D12) (Biotin)
423
CHF
CHF 423.00
In stock
ANC-250-030100 µgCHF 423.00
| Product Details | |
|---|---|
| Synonyms | TRAMP; Apo-3; Death Receptor 3; WSL-1; Lymphocyte-associated Receptor of Death; LARD; Tumor Necrosis Factor Receptor Superfamily Member 25; TNFRSF25 |
| Product Type | Monoclonal Antibody |
| Properties | |
| Clone | ANC2D12 |
| Isotype | Mouse IgG1κ |
| Immunogen/Antigen | Recombinant DR3. |
| Label/Conjugates | Biotin |
| Application |
ELISA |
| Crossreactivity | Human |
| Formulation | 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative). |
| Isotype Negative Control | |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by Ancell Corporation. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at +4°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Human DR3 (TRAMP; LARD) was designated TNF receptor superfamily member 25. TL1A is a ligand which can induce apoptosis through a cytoplasmic death domain similar to the CD178-CD95 (FasL-Fas) interaction. Alternatively, engagement of DR3 on T cells can synergize with other activating signals to enhance IFNγ production.
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