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Bertin Bioreagent
anti-TAF10, mAb (2F4)
As low as
664
CHF
CHF 664.00
In stock
Only %1 left
BRT-G01076-R100100 µlCHF 664.00
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| Product Details | |
|---|---|
| Synonyms | Transcription Initiation Factor TFIID Subunit 10; STAF28; TATA-Box Binding Protein-Associated Factor 10; TAFII30 |
| Product Type | Monoclonal Antibody |
| Properties | |
| Clone | 2F4 |
| Isotype | Mouse IgG1κ |
| Source/Host | Mouse |
| Immunogen/Antigen | Full length human TAFII30 as a fusion protein. |
| Application | ELISA, Western Blot (endogenous and recombinant proteins), Immunocytofluorescence, Immunoprecipitation (works efficiently, but cannot be eluted with the peptide corresponding to the epitope). Recommended dilutions: 1/500-1/5000. |
| Specificity | Recognizes human TAF10 (GGPGAGAAAGGTG epitope from aa 50 to 62. Does not work on mouse. |
| Formulation | Liquid. Does not contain any preservative. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by Bertin Bioreagent |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 3 years after receipt when stored at -20°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
TAF10 is a transcription cofactor and a component of the Transcription Factor IID (TFIID) complex, which is essential for RNA polymerase II-dependent transcription initiation. TAF10 is a core component of TFIID, a multi-protein complex that recognizes promoter DNA and recruits RNA polymerase II to initiate transcription. TAF10 is also a part of the SAGA (Spt-Ada-Gcn5 Acetyltransferase) complex, which regulates gene expression through histone acetylation. TAF10 is essential for embryonic development and plays a role in cell fate decisions. TAF10 mutations or dysregulation can impact gene expression in cancers and developmental disorders.