BioViotica

Resistomycin

CHF 115.00
In stock
BVT-0036-M0011 mgCHF 115.00
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Product Details
Synonyms Geliomycin; Heliomycin; Itamycin; 3,5,7,10-Tetrahydroxy-1,1,9-trimethyl-1H-benzo-[cd]pyrene-2,6-dione
Product Type Chemical
Properties
Formula

C22H16O6

MW 376.4
CAS 20004-62-0
RTECS DJ6350000
Source/Host Chemicals Isolated from Streptomyces sp.
Purity Chemicals ≥98% (HPLC)
Appearance Yellow to orange solid.
Solubility Soluble in DMSO or methanol.
Identity Determined by 1H-NMR.
Declaration Manufactured by BioViotica.
InChi Key ABLACSIRCKEUOB-UHFFFAOYSA-N
Smiles CC1=CC(O)=C2C(=O)C3=C4C(=C(O)C=C3O)C(=O)C(C)(C)C3=C4C2=C1C(O)=C3
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
After reconstitution protect from light at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description
  • Antibacterial (Gram-positive and mycobacteria) and antiviral.
  • RNA polymerase inhibitor.
  • Anticancer compound. Apoptosis inducer.
Product References
  1. Effects of the antibiotic resistomycin on the synthesis of macromolecules: I. Haupt, et al.; Z. Allg. Mikrobiol. 156, 411 (1975)
  2. 3-Alkanoyl-5-hydroxymethyl tetronic acid homologues and resistomycin: new inhibitors of HIV-1 protease. I. Fermentation, isolation and biological activity: B.E. Roggo, et al.; J. Antibiot. 47, 136 (1994)
  3. Effects of polyphenolic anthrone derivatives, resistomycin and hypericin, on apoptosis in human megakaryoblastic leukemia CMK-7 cell line: Y. Shiono et al.; Z. Naturforsch. 57c, 923 (2002)
  4. Assessment of resistomycin, as an anticancer compound isolated and characterized from Streptomyces aurantiacus AAA5: R. Vijayabharathi, et al.; J. Microbiol. 49, 920 (2011)
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