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BioViotica
Resistomycin
115
CHF
CHF 115.00
In stock
BVT-0036-M0011 mgCHF 115.00
Product Details | |
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Synonyms | Geliomycin; Heliomycin; Itamycin; 3,5,7,10-Tetrahydroxy-1,1,9-trimethyl-1H-benzo-[cd]pyrene-2,6-dione |
Product Type | Chemical |
Properties | |
Formula |
C22H16O6 |
MW | 376.4 |
CAS | 20004-62-0 |
RTECS | DJ6350000 |
Source/Host Chemicals | Isolated from Streptomyces sp. |
Purity Chemicals | ≥98% (HPLC) |
Appearance | Yellow to orange solid. |
Solubility | Soluble in DMSO or methanol. |
Identity | Determined by 1H-NMR. |
Declaration | Manufactured by BioViotica. |
InChi Key | ABLACSIRCKEUOB-UHFFFAOYSA-N |
Smiles | CC1=CC(O)=C2C(=O)C3=C4C(=C(O)C=C3O)C(=O)C(C)(C)C3=C4C2=C1C(O)=C3 |
Shipping and Handling | |
Shipping | BLUE ICE |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C. |
Documents | |
MSDS | Download PDF |
Product Specification Sheet | |
Datasheet | Download PDF |
Description
- Antibacterial (Gram-positive and mycobacteria) and antiviral.
- RNA polymerase inhibitor.
- Anticancer compound. Apoptosis inducer.
Product References
- Effects of the antibiotic resistomycin on the synthesis of macromolecules: I. Haupt, et al.; Z. Allg. Mikrobiol. 156, 411 (1975)
- 3-Alkanoyl-5-hydroxymethyl tetronic acid homologues and resistomycin: new inhibitors of HIV-1 protease. I. Fermentation, isolation and biological activity: B.E. Roggo, et al.; J. Antibiot. 47, 136 (1994)
- Effects of polyphenolic anthrone derivatives, resistomycin and hypericin, on apoptosis in human megakaryoblastic leukemia CMK-7 cell line: Y. Shiono et al.; Z. Naturforsch. 57c, 923 (2002)
- Assessment of resistomycin, as an anticancer compound isolated and characterized from Streptomyces aurantiacus AAA5: R. Vijayabharathi, et al.; J. Microbiol. 49, 920 (2011)