Acetomycin

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Product Details
Synonyms	NSC350598; 3-Acetyl-5-(acetyloxy)dihydro-3,4-dimethyl-2(3H)furanone; (2R,3S,4S)-4-Acetyl-3,4-dimethyl-5-oxotetrahydro-furan-2-yl acetate
Product Type	Chemical
Properties
Formula	C₁₀H₁₄O₅
MW	214.2
CAS	510-18-9
Source/Host Chemicals	Isolated from Streptomyces ramulosus.
Purity Chemicals	≥98% (HPLC)
Appearance	White to off-white crystalline solid.
Solubility	Soluble in DMSO or methanol.
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by BioViotica.
InChi Key	OYMZTORLGBISLR-RHFNHBFPSA-N
Smiles	C[C@@H]1[C@H](OC(C)=O)OC(=O)[C@]1(C)C(C)=O
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Use/Stability	Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
Documents
MSDS	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Description

Product References

The structure of acetomycin. Spectroscopic characterization and X-ray analysis of a bromo derivative: H. Uhr, et al.; J. Antibiot. 38, 1684 (1985)
Biological effects of acetomycin. I. Activity against tumor cells in vitro and in vivo: S.W. Mamber, et al.; J. Antibiot. 40, 73 (1987)
Biological effects of acetomycin. II. Inactivation by esterases in vitro: S.W. Mamber, et al.; J. Antibiot. 40, 77 (1987)
The structure and absolute configuration of acetomycin: F.H. Cano, et al.; Acta Cryst. C. 44, 919 (1988).
Synthesis and in vitro cytotoxicity of acetomycin and related analogs: D. Chen, et al.; Bioorg. Med. Chem. Lett. 5, 759 (1995)
Total synthesis of (±)-acetomycin and design of esterase-resistant analogs: J. Uenishi, et al.; Chem. Pharm. Bull. 47, 517 (1999)
Formation of chiral quaternary carbon stereocenters using silylene transfer reactions: Enantioselective synthesis of (+)-5-epi-acetomycin: S.A. Calad, et al.; Org. Lett. 9, 1037 (2007)

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