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BioViotica
Acetomycin
115
CHF
CHF 115.00
In stock
BVT-0150-M0011 mgCHF 115.00
BVT-0150-M0055 mgCHF 385.00
| Product Details | |
|---|---|
| Synonyms | NSC350598; 3-Acetyl-5-(acetyloxy)dihydro-3,4-dimethyl-2(3H)furanone; (2R,3S,4S)-4-Acetyl-3,4-dimethyl-5-oxotetrahydro-furan-2-yl acetate |
| Product Type | Chemical |
| Properties | |
| Formula |
C10H14O5 |
| MW | 214.2 |
| CAS | 510-18-9 |
| Source/Host Chemicals | Isolated from Streptomyces ramulosus. |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | White to off-white crystalline solid. |
| Solubility | Soluble in DMSO or methanol. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by BioViotica. |
| InChi Key | OYMZTORLGBISLR-RHFNHBFPSA-N |
| Smiles | C[C@@H]1[C@H](OC(C)=O)OC(=O)[C@]1(C)C(C)=O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Antibiotic.
- Antibacterial, antifungal and antiprotozoal.
- Cytotoxic against several tumor cell lines in vitro.
Product References
- The structure of acetomycin. Spectroscopic characterization and X-ray analysis of a bromo derivative: H. Uhr, et al.; J. Antibiot. 38, 1684 (1985)
- Biological effects of acetomycin. I. Activity against tumor cells in vitro and in vivo: S.W. Mamber, et al.; J. Antibiot. 40, 73 (1987)
- Biological effects of acetomycin. II. Inactivation by esterases in vitro: S.W. Mamber, et al.; J. Antibiot. 40, 77 (1987)
- The structure and absolute configuration of acetomycin: F.H. Cano, et al.; Acta Cryst. C. 44, 919 (1988).
- Synthesis and in vitro cytotoxicity of acetomycin and related analogs: D. Chen, et al.; Bioorg. Med. Chem. Lett. 5, 759 (1995)
- Total synthesis of (±)-acetomycin and design of esterase-resistant analogs: J. Uenishi, et al.; Chem. Pharm. Bull. 47, 517 (1999)
- Formation of chiral quaternary carbon stereocenters using silylene transfer reactions: Enantioselective synthesis of (+)-5-epi-acetomycin: S.A. Calad, et al.; Org. Lett. 9, 1037 (2007)
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