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BioViotica
Zearalenone
80
CHF
CHF 80.00
In stock
BVT-0394-M0055 mgCHF 80.00
| Product Details | |
|---|---|
| Synonyms | Toxin F2; BRN 1350216; FES; NCI-C50226; Zenone |
| Product Type | Chemical |
| Properties | |
| Formula |
C18H22O5 |
| MW | 318.4 |
| Merck Index | 13: 10169 |
| CAS | 17924-92-4 |
| Source/Host Chemicals | Isolated from Fusarium graminearum. |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | Off-white solid. |
| Solubility | Soluble in DMSO, methanol or acetone. |
| Identity | Determined by 1H-NMR and UV. |
| Declaration | Manufactured by BioViotica. |
| InChi Key | MBMQEIFVQACCCH-QBODLPLBSA-N |
| Smiles | C[C@H]1CCCC(=O)CCC\C=C\C2=CC(O)=CC(O)=C2C(=O)O1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Keep cool and dry. |
| Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Resorcylic acid lactone.
- Mycotoxin.
- Regulator of fungal morphogenesis.
- Mycoestrogen with anabolic and uterotrophic activity.
- Ecdysteroid antagonist.
- Gonadotropin inhibitor.
- Interleukin antagonist.
- Apoptosis inducer.
- Analytical standard in food industry.
Product References
- The structure of zearalenone: W. H. Urry, et al.; Tetrahedron Lett. 1966, 3109 (1966)
- Physicochemical data for some selected mycotoxins: A E. Pohland, et al.; Pure Appl. Chem. 54, 2219 (1982)
- Zearalenone: K. Panneerselvam, et al.; Acta Cryst. C52, 3095 (1996)
- The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor: X. Ding, et al.; Toxicol. Sci. 91, 448 (2006)
- Trace mycotoxin analysis in complex biological and food matrices by liquid chromatography-atmospheric pressure ionisation mass spectrometry: P. Zollner & B. Mayer-Helm; J. Chromatogr. A 1136, 123 (2006)
- The PKS4 gene of Fusarium graminearum is essential for zearalenone production: E. Lysoe, et al; Appl. Environ. Microbiol. 72, 3924 (2006)
- Chemistry and biology of resorcyclic acid lactones: N. Winssinger & S. Barluenga; Chem. Commun. 2007, 22 (2007)
- Review on the toxicity, occurrence, metabolism, detoxification, regulations and intake of zearalenone: an oestrogenic mycotoxin: A. Zinedine, et al.; Food Chem. Toxicol. 45, 1 (2007)
- Biomimetic synthesis of resorcylate natural products utilizing late stage aromatization: concise total syntheses of the marine antifungal agents 15G256ι and 15G256β: I. Navarro, et al.; JACS 130, 10293 (2008)
- Effects of exposure to zearalenone on porcine oocytes and sperm during maturation and fertilization in vitro: R. Sambuu, et al.; J. Reprod. Dev. 57, 547 (2011)
- Fusarium graminearum mycotoxins and their biosynthetic genes: H. Son & Y.-W. Lee; Mycotoxins 62, 29 (2012)
- Zearalenone induces apoptosis and necrosis in porcine granulose cells via a caspase-3- and caspase-9-dependent mitochondrial signaling pathway: L. Zhu, et al.; J. Cell. Physiol. 227, 1814 (2012)
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