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Cayman
Cl-Amidine (hydrochloride)
75
CHF
CHF 75.00
In stock
CAY-10599-11 mgCHF 75.00
CAY-10599-55 mgCHF 226.00
CAY-10599-1010 mgCHF 340.00
| Product Details | |
|---|---|
| Product Type | Chemical |
| Properties | |
| Formula | C14H19ClN4O2 . HCl |
| MW | 347.2 |
| CAS | 1373232-26-8 |
| Purity Chemicals | ≥95% |
| Appearance | A crystalline solid |
| Declaration | Manufactured by Cayman Chemicals. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | OPFMEGSAOZAJIV-MERQFXBCSA-N |
| Smiles | O=C(N[C@@H](CCCNC(CCl)=N)C(N)=O)C1=CC=CC=C1.Cl |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
An inhibitor of PAD4 deimination activity (IC50 = 5.9 µM) that also inhibits PAD1 and PAD3 (IC50 = 0.8 and 6.2 µM, respectively); dose dependently decreases the citrulline content in serum and joints and reduces the development of IgG autoantibodies in a CIA mouse model of inflammatory arthritis.