Cookie Policy: This site uses cookies to improve your experience. You can find out more about our use of cookies in our Privacy Policy. By continuing to browse this site you agree to our use of cookies.
Cayman
DMXAA
49
CHF
CHF 49.00
In stock
CAY-14617-11 mgCHF 49.00
CAY-14617-55 mgCHF 108.00
CAY-14617-1010 mgCHF 188.00
CAY-14617-2525 mgCHF 411.00
| Product Details | |
|---|---|
| Synonyms | 5,6-Dimethylxanthenone-4-acetic Acid; ASA 404; NSC 640488; Vadimezan |
| Product Type | Chemical |
| Properties | |
| Formula | C17H14O4 |
| MW | 282.3 |
| CAS | 117570-53-3 |
| Purity Chemicals | ≥98% |
| Appearance | A crystalline solid |
| Declaration | Manufactured by Cayman Chemicals. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | XGOYIMQSIKSOBS-UHFFFAOYSA-N |
| Smiles | O=C1C2=C(C(CC(O)=O)=CC=C2)OC3=C(C)C(C)=CC=C31 |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
A tumor vascular disrupting agent, inducing apoptosis in tumor vascular endothelium resulting in necrosis at the tumor core; potently activates the STING/TBK1/IRF3 signaling pathway in mouse leukocytes, inducing type-I-IFN production; inhibits VEGFR1 and VEGFR2 (IC50 = 119 and 11 µM, respectively).