Cookie Policy: This site uses cookies to improve your experience. You can find out more about our use of cookies in our Privacy Policy. By continuing to browse this site you agree to our use of cookies.
Cayman
dsDNA Monoclonal Antibody (Clone 2C4)
485
CHF
CHF 485.00
In stock
CAY-15635-11 eaCHF 485.00
| Product Details | |
|---|---|
| Synonyms | double-stranded DNA |
| Product Type | Monoclonal Antibody |
| Properties | |
| Clone | 2C4 |
| Isotype | IgM |
| Application | ELISA, FC, IF |
| Crossreactivity |
Human Mouse |
| Specificity | Recognizes human and mouse dsDNA. |
| Formulation | 200 µg of ammonium sulfate-purified monoclonal antibody |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by Cayman Chemicals. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
In response to stimuli, neutrophils have the ability to release net-like structures containing nuclear DNA, de-condensed histones, and antimicrobial peptides. These neutrophil extracellular traps (NETs) have the ability to contact and kill pathogens including fungi, bacteria, and protozoa; they are then rapidly cleared by the immune system. However, in aged NZBWF1 mice and human lupus patients, the clearance is delayed, allowing formation of antibodies to these NET components.