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Cayman
GSK484 (hydrochloride)
57
CHF
CHF 57.00
In stock
CAY-17488-500500 µgCHF 57.00
CAY-17488-11 mgCHF 105.00
CAY-17488-55 mgCHF 436.00
CAY-17488-1010 mgCHF 761.00
Product Details | |
---|---|
Product Type | Chemical |
Properties | |
Formula | C27H31N5O3 . HCl |
MW | 510 |
CAS | 1652591-81-5 |
Purity Chemicals | ≥95% |
Appearance | A crystalline solid |
Declaration | Manufactured by Cayman Chemicals. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | MULKOGJHUZTANI-ADMBKAPUSA-N |
Smiles | O[C@@H]1CCN(C(C2=CC(N=C(C3=CC(C=CC=C4)=C4N3CC5CC5)N6C)=C6C(OC)=C2)=O)C[C@@H]1N.Cl |
Shipping and Handling | |
Shipping | BLUE ICE |
Long Term Storage | -20°C |
Documents | |
MSDS | Inquire |
Product Specification Sheet | |
Datasheet | Download PDF |
Description
A reversible inhibitor of PAD4 (IC50 = 50 nM) that binds to the low-calcium form of the enzyme; blocks the citrullination of PAD4 target proteins in human neutrophils and inhibits the formation of NETs in both mouse and human neutrophils.