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Cayman
2'3'-cGAMP (sodium salt)
425
CHF
CHF 425.00
In stock
CAY-19887-500500 µgCHF 425.00
CAY-19887-11 mgCHF 804.00
| Product Details | |
|---|---|
| Synonyms | 2'-3'-Cyclic GMP-AMP; Guanosine-Adenosine 2',3'-cyclic monophosphate |
| Product Type | Chemical |
| Properties | |
| Formula | C20H22N10O13P2 . 2Na |
| MW | 718.4 |
| Purity Chemicals | ≥98% |
| Appearance | A solid |
| Declaration | Manufactured by Cayman Chemicals. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | CNVCOPPPOWRJAV-DQNSRKNCSA-L |
| Smiles | O=P1([O-])O[C@]([C@@H](O)[C@H](N2C=NC3=C2N=CN=C3N)O4)([H])[C@@]4([H])COP(O[C@@]5([H])[C@H](N6C=NC7=C6NC(N)=NC7=O)O[C@]([C@H]5O)([H])CO1)([O-])=O.[Na+].[Na+] |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
A second messenger produced from ATP and GTP by cGMP-AMP synthase (cGAS) in the cytoplasm of mammalian cells in response to the presence of DNA; binds tightly to the adapter protein STING (Kd = 3.79 nM) and induces IFN-β production (EC50 = 19.4 nM in L929 cells).