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Cayman
Myeloperoxidase (mouse) Polyclonal Antibody
616
CHF
CHF 616.00
In stock
CAY-20493-11 eaCHF 616.00
| Product Details | |
|---|---|
| Synonyms | MPO |
| Product Type | Polyclonal Antibody |
| Properties | |
| Application | ELISA, WB |
| Specificity | For immunochemical detection of MPO |
| Formulation | 500 µl of protein A-purified IgG |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by Cayman Chemicals. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Myeloperoxidase (MPO) is one of the most abundant proteins in neutrophils comprising 5% of the dry weight of the cell. MPO is stored in the azurophilic granules and released when neutrophils are stimulated. MPO catalyzes the oxidation of chloride and other halide ions in the presence of hydrogen peroxide to generate hypochlorous acid and other antimicrobial products. MPO is required for the neutrophil extracellular trap (NETs) response. Activated neutrophils die and release NETs which are composed of decondensed chromatin and anti-microbial proteins including MPO.