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Cayman
G10
51
CHF
CHF 51.00
In stock
CAY-22353-11 mgCHF 51.00
CAY-22353-55 mgCHF 165.00
CAY-22353-1010 mgCHF 253.00
| Product Details | |
|---|---|
| Synonyms | STING Agonist-1 |
| Product Type | Chemical |
| Properties | |
| Formula | C21H16ClFN2O3S |
| MW | 430.9 |
| CAS | 702662-50-8 |
| Purity Chemicals | ≥98% |
| Appearance | A crystalline solid |
| Declaration | Manufactured by Cayman Chemicals. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | NAGKYJATVFXZKN-UHFFFAOYSA-N |
| Smiles | O=C1CSC2=C(C=C(C(NCC3=CC=CO3)=O)C=C2)N1CC4=C(Cl)C=CC=C4F |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
An indirect activator of STING signaling; induces IRF3- and IFN-dependent transcription in human fibroblasts, PBMCs, and HUMECs; prevents replication of chikungunya and Venezuelan equine encephalitis alphaviruses (IC90s = 8.01 and 24.57 µM, respectively); increases phosphorylation of IRF3 when used at a concentration of 100 µM but not in cells lacking STING.