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Cayman
2'2'-cGAMP (sodium salt)
650
CHF
CHF 650.00
In stock
CAY-22419-500500 µgCHF 650.00
CAY-22419-11 mgCHF 1'100.00
| Product Details | |
|---|---|
| Synonyms | 2',2'-Cyclic GMP-AMP; Adenosine-Guanosine 2',2'-cyclic monophosphate; cGAMP(2'-5') |
| Product Type | Chemical |
| Properties | |
| Formula | C20H22N10O13P2 . 2Na |
| MW | 718.4 |
| CAS | 1465774-27-9 |
| Purity Chemicals | ≥98% |
| Appearance | A crystalline solid |
| Declaration | Manufactured by Cayman Chemicals. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | SCPBVQDKYSCDAE-RENITANYSA-N |
| Smiles | O=P(OC[C@](O[C@H]1N2C=NC3=C2NC(N)=NC3=O)([H])C(O)[C@@]1([H])O4)([O-])O[C@]([C@H](N5C=NC6=C5N=CN=C6N)O7)([H])C(O)[C@@]7([H])COP4([O-])=O.[Na+].[Na+] |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
A second messenger produced from ATP and GTP by cGAS; binds the adapter protein STING (Kd = 287 nM); induces IFN-β production (EC50 = 15.8 nM in L929 cells).