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Cayman
TBK1 (human, recombinant)
1030
CHF
CHF 1'030.00
In stock
CAY-22817-5050 µgCHF 1'030.00
| Product Details | |
|---|---|
| Synonyms | NAK; NF-κB-Activating Kinase; TANK-Binding Kinase 1 |
| Product Type | Protein |
| Properties | |
| Sequence | Human recombinant protein expressed in insect cells (baculovirus). |
| Purity | ≥50% (SDS-PAGE) |
| Formulation | 50 mM HEPES, pH 8.0, with 150 mM sodium chloride, and 10% glycerol |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by Cayman Chemicals. |
| Shipping and Handling | |
| Shipping | DRY ICE |
| Long Term Storage | -80°C |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
A noncanonical IKK that has an essential role in regulating inflammatory responses to pathogens; interacts with STING, MAVS, and TANK to phosphorylate and activate IRF3, IRF7, and DDX3X which leads to transcriptional activation of IFN-α and β; phosphorylates the autophagy receptor optineurin to enhance binding of LC3 modifiers and induce autophagic clearance of S. enterica.