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Cayman
ML RR-S2 CDA (ammonium salt)
1198
CHF
CHF 1'198.00
In stock
CAY-24106-500500 µgCHF 1'198.00
CAY-24106-11 mgCHF 1'793.00
| Product Details | |
|---|---|
| Synonyms | STING Inducer-1 |
| Product Type | Chemical |
| Properties | |
| Formula | C20H22N10O10P2S2 . 2NH4 |
| MW | 724.6 |
| CAS | 1638750-96-5 |
| Purity Chemicals | ≥98% |
| Appearance | A solid |
| Declaration | Manufactured by Cayman Chemicals. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | VZYXAGGQHVUTHM-ITQXCAEYSA-N |
| Smiles | O[C@@H]([C@H](N1C=NC2=C(N)N=CN=C21)O3)[C@@](O[P@@]4([S-])=O)([H])[C@@]3([H])CO[P@](O[C@@]5([H])[C@H](N6C=NC7=C(N)N=CN=C76)O[C@@]([H])([C@]5(O)[H])CO4)([S-])=O.[NH4+].[NH4+] |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
An activator of STING; induces expression of IFN-β and the pro-inflammatory cytokines TNF-α, IL-6, and Mcp-1 in murine BMMs isolated from wild-type, but not STING-/-, mice; induces IFN-β expression in PBMCs isolated from donors carrying STINGWT/WT, STINGWT/REF, and STINGWT/HAQ alleles; initiates tumor regression and prevents tumor growth upon tumor cell reimplantation in 4T1 breast and CT26 colon cancer mouse xenograft models.