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Cayman
C-178
49
CHF
CHF 49.00
In stock
CAY-25860-55 mgCHF 49.00
CAY-25860-1010 mgCHF 94.00
CAY-25860-2525 mgCHF 214.00
CAY-25860-5050 mgCHF 354.00
| Product Details | |
|---|---|
| Product Type | Chemical |
| Properties | |
| Formula | C17H10N2O5 |
| MW | 322.3 |
| CAS | 329198-87-0 |
| Purity Chemicals | ≥98% |
| Appearance | A crystalline solid |
| Declaration | Manufactured by Cayman Chemicals. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | URUVDCCYSJEGQQ-UHFFFAOYSA-N |
| Smiles | O=C(NC1=CC=C(C(C=CC=C2)=C2O3)C3=C1)C4=CC=C([N+]([O-])=O)O4 |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
A STING inhibitor; binds to Cys91 on STING to block its and prevents recruitment and phosphorylation of TBK1 in HEK293T cells; selectively reduces STING-, but not RIG-I- or TBK1-, mediated IFN-β reporter activity in HEK293 cells from 0.01-1.25 µM; prevents increases in Ifnb1 expression induced by cyclic di-GMP, double-stranded DNA, and LPS in BMDMs at 0.5 µM.