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Cayman
GW 311616A
125
CHF
CHF 125.00
In stock
CAY-27957-11 mgCHF 125.00
CAY-27957-55 mgCHF 367.00
CAY-27957-1010 mgCHF 610.00
| Product Details | |
|---|---|
| Product Type | Chemical |
| Properties | |
| Formula | C19H31N3O4S . HCl |
| MW | 434 |
| CAS | 197890-44-1 |
| Purity Chemicals | ≥95% |
| Appearance | A crystalline solid |
| Declaration | Manufactured by Cayman Chemicals. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | UFCZUKYPBPXODT-OFTZGUNKSA-N |
| Smiles | O=C(N1CC[C@](N2S(C)(=O)=O)([H])[C@]1([H])[C@H](C(C)C)C2=O)/C=C/CN3CCCCC3.Cl |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
An inhibitor of neutrophil elastase (Ki = 0.31 nM); selective for human neutrophil elastase (IC50 = 22 nM) over trypsin, cathepsin G, and plasmin (IC50s = >100 µM for all), as well as chymotrypsin and tissue plasminogen activator (IC50s >3 µM for all), in a cell-free assay; inhibits neutrophil elastase activity in isolated dog whole blood and in the liver in a mouse model of liver ischemia-reperfusion injury at 2 mg/kg.