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Cayman
Ac-FLTD-CMK (trifluoroacetate salt)
655
CHF
CHF 655.00
In stock
CAY-34469-11 mgCHF 655.00
CAY-34469-55 mgCHF 2'935.00
| Product Details | |
|---|---|
| Synonyms | Ac-Phe-Leu-Thr-Asp-CMK |
| Product Type | Chemical |
| Properties | |
| Formula | C26H37ClN4O8 . XCF3COOH |
| MW | 569 |
| Purity Chemicals | ≥95% |
| Appearance | A solid |
| Declaration | Manufactured by Cayman Chemicals. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | XJCUHBUOWTWTOV-DXXINTPRSA-N |
| Smiles | ClCC([C@H](CC(O)=O)NC([C@H]([C@H](O)C)NC([C@H](CC(C)C)NC([C@@H](NC(C)=O)CC1=CC=CC=C1)=O)=O)=O)=O.FC(F)(F)C(O)=O |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
An inhibitor of caspase-1, -4, -5, and -11; inhibits caspase-1, -4, and -5 (IC50s = 0.0467, 1.49, and 0.329, respectively, for the recombinant human enzymes) and cleavage of GSDMD by mouse caspase-11 at 10 µM; inhibits LPS- and ATP- or LPS- and nigericin-induced pyroptosis and IL-1β release in mouse BMDMs.