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Cayman
M04
185
CHF
CHF 185.00
In stock
CAY-35454-500500 µgCHF 185.00
CAY-35454-11 mgCHF 350.00
| Product Details | |
|---|---|
| Product Type | Chemical |
| Properties | |
| Formula | C18H24N2O4S3 |
| MW | 428.6 |
| CAS | 875158-73-9 |
| Purity Chemicals | ≥98% |
| Appearance | A crystalline solid |
| Declaration | Manufactured by Cayman Chemicals. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | ZPAFZCRZMRTBGW-UHFFFAOYSA-N |
| Smiles | O=S(C1=CC=C(C)C=C1)(C2=C(N(C)C)SC(S(=O)(C3CCCCC3)=O)=N2)=O |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
A STING agonist; induces IFN reporter gene expression in HEK293T cells expressing wild-type human STING but not in HEK293T cells expressing the HAQ human STING variant nor in mouse RAW 264.7 cells at 75 µM; induces the production of TNF-α, IL-10, IL-1β, and IL-12p70 in human PBMCs; increases the percentage of isolated human monocyte-derived dendritic cells expressing HLA-DR, CD40, CD80, and CD86, as well as increases T cell cross-priming of the same cells in an ex vivo assay, at 50 µM.