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Cayman
KAS 08
166
CHF
CHF 166.00
In stock
CAY-36474-11 mgCHF 166.00
CAY-36474-55 mgCHF 741.00
CAY-36474-1010 mgCHF 1'397.00
| Product Details | |
|---|---|
| Product Type | Chemical |
| Properties | |
| Formula | C24H20N4O6S |
| MW | 492.5 |
| CAS | 203861-20-5 |
| Purity Chemicals | ≥95% |
| Appearance | A solid |
| Declaration | Manufactured by Cayman Chemicals. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | PHTUTOMJUWFHHH-OAQYLSRUSA-N |
| Smiles | O=C(C1=CC=C([N+]([O-])=O)C=C1)N2CCC3=CC(S(=O)(N4C(N[C@](C5=CC=CC=C5)([H])C4)=O)=O)=CC=C32 |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
A STING activator (EC50 = 0.33 µM in a reporter assay using THP-1 human monocytes); increases IFN-β and IP-10 levels in the presence, but not absence, of cGAMP; reduces the viability of CT26 cells at 0.31-20 µM; reduces tumor growth in a CT26 mouse syngeneic model at 15 mg/kg when used in combination with 2'3'-cGAMP.