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Cayman
Diphenyleneiodonium (chloride)
68
CHF
CHF 68.00
In stock
CAY-81050-55 mgCHF 68.00
CAY-81050-1010 mgCHF 108.00
| Product Details | |
|---|---|
| Synonyms | DPI |
| Product Type | Chemical |
| Properties | |
| Formula | C12H8I . Cl |
| MW | 314.5 |
| CAS | 4673-26-1 |
| Purity Chemicals | ≥99% |
| Appearance | A crystalline solid |
| Declaration | Manufactured by Cayman Chemicals. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | FCFZKAVCDNTYID-UHFFFAOYSA-M |
| Smiles | C12=C(C3=C([I+]2)C=CC=C3)C=CC=C1.[Cl-] |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Long Term Storage | +20°C |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
DPI is an irreversible inhibitor of iNOS and eNOS with IC50 values of 50 nM and 0.3 µM, respectively. This inhibition is potent, irreversible, and time and temperature dependent. NADPH, NADP+, and 2'5'-ADP block the inhibitory action of DPI. Similarly, FAD or FMN protect NOS from inhibition by DPI.