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Chemodex
3-Acetyl-7-hydroxycoumarin
245
CHF
CHF 245.00
In stock
CDX-A0003-M500500 mgCHF 245.00
CDX-A0003-G0011 gCHF 387.00
| Product Details | |
|---|---|
| Synonyms | 3-Acetylumbelliferone; 3-Acetyl-7-hydroxy-2H-chromen-2-one; AHC |
| Product Type | Chemical |
| Properties | |
| Formula | C11H8O4 |
| MW | 204.18 |
| CAS | 10441-27-7 |
| Source/Host Chemicals | Synthetic |
| Purity Chemicals | ≥.97% (NMR) |
| Appearance | Yellow powder. |
| Solubility | Soluble in DMSO. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | BRQZHMHHZLRXOO-UHFFFAOYSA-N |
| Smiles | O=C1OC2=C(C=C1C(C)=O)C=CC(O)=C2 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
3-Acetyl-7-hydroxycoumarin is a pH-sensitive fluorescent indicator dye. Has been shown to be a macrophage migration inhibitory factor (MIF) active compound. Important heterocyclic building block and intermediate used for synthesis of fluorescent probes and bioactive compounds. Spectral data: Absorption: 413nm; Excitation: 419nm; Fluorescence: 458nm (in H2O).
Product References
(1) S. Rangaswami, et al.; Proc. Ind. Acad. Sci. 13, 316 (1941) | (2) C.E. Wheelock; JACS 81, 1348 (1959) | (3) W.R. Sherman & E. Robins; Anal. Chem. 40, 803 (1968) | (4) M. Orita, et al.; J. Med. Chem. 44, 540 (2001) | (5) K. Azuma, et al.; Photochem. Photobiol. Sci. 2, 443 (2003) | (6) J.R. Fry, et al.; Xenobiotica 34, 707 (2004) | (7) Y-F. Sun & Y-P. Cui; Dyes Pigm. 78, 65 (2008) | (8) O. Garcia-Beltran, et al.; Tetrahedr. Lett. 52, 6606 (2011) | (9) M. Khoobi, et al.; Arch. Pharm. 344, 588 (2011) | (10) O. Garcia-Beltran, et al.; Eur. J. Med. Chem. 76, 79 (2014) | (11) X. Dai, et al.; Biosens. Bioelectr. 59, 35 (2014) | (12) D. Tao, et al.; Eur. J. Med. Chem. 173, 203 (2019) | (13) L. Fu, et al.; Microchim. Acta 186, 491 (2019) | (14) J. Wang, et al.; Talanta 205, 120095 (2019) | (15) K. Wang, et al.; Biosensors 13, 658 (2023)