N4-Acetylsulfamethoxazole

CHF 64.00
In stock
CDX-A0291-M01010 mgCHF 64.00
CDX-A0291-M05050 mgCHF 191.00
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Product Details
Synonyms N-{4-{[(5-Methyl-3-isoxazolyl)amino]sulfonyl}phenyl}acetamide; Sulfisomezole-N4-acetate; BRN 0285801; STX 606
Product Type Chemical
Properties
Formula

C12H13N3O4S

MW 295.3
CAS 21312-10-7
Source/Host Chemicals Synthetic.
Purity Chemicals ≥99% (HPLC)
Appearance White to off-white powder or crystals.
Solubility Soluble in chloroform.
Identity Determined by NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key GXPIUNZCALHVBA-UHFFFAOYSA-N
Smiles CC(=O)NC1=CC=C(C=C1)S(=O)(=O)NC1=NOC(C)=C1
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
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Product Specification Sheet
Datasheet Download PDF

This is a metabolite of the sulfonamide bacteriostatic antibiotic sulfamethoxazole. Sulfamethoxazole is metabolized via acetylation, catalyzed by liver extramitochondrial N-acetyl transferases. Acetyl-Sulfamethoxazole is excreted in urine. Both compounds can be used as a probe for the molecular percentage enrichement of liver extramitochondrial acetyl-CoA. Acetyl-Sulfamethoxazole can also be used as a reference for sulfamethoxazole impurity and waste determination.

Product References

(1) T.B. Vree, et al.; Clin. Pharmacokinet. 3, 319 (1978) | (2) R.M. Hutabarat, et al.; Clin. Pharmacol. Ther. 49, 402 (1991) | (3) T. Heberer, et al.; Toxicol. Lett. 131, 5 (2002) | (4) T.A. Larsen, et al.; J. Biotechnol. 113, 295 (2004) | (5) K. Stein, et al.; Environ. Sci. Technol. 42, 6415 (2008)

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