Cookie Policy: This site uses cookies to improve your experience. You can find out more about our use of cookies in our Privacy Policy. By continuing to browse this site you agree to our use of cookies.
Chemodex
Ampicilline sodium salt
Product Details | |
---|---|
Synonyms | D-(-)-α-Aminobenzylpenicillin sodium salt |
Product Type | Chemical |
Properties | |
Formula | C16H18N3NaO4S |
MW | 371.39 |
CAS | 69-52-3 |
RTECS | XH8400000 |
Source/Host Chemicals | Synthetic |
Purity Chemicals | ≥85% (HPLC) |
Appearance | White to slight yellow powder. |
Solubility | Soluble in water (20 mg/ml). Soluble in DMSO or DMF (both 10mg/ml). |
Identity | Determined by 1H-NMR. |
Declaration | Manufactured by Chemodex. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | KLOHDWPABZXLGI-YWUHCJSESA-M |
Smiles | O=C1[C@@H](NC([C@H](N)C2=CC=CC=C2)=O)[C@]3([H])N1[C@@H](C([O-])=O)C(C)(C)S3.[Na+] |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +20°C |
Long Term Storage | +4°C |
Handling Advice |
Keep under inert gas. Very hygroscopic. |
Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
Documents | |
MSDS | Inquire |
Product Specification Sheet | |
Datasheet | Download PDF |
Ampicillin is a broad-spectrum antibiotic with activity against Gram-positive and Gram-negative bacteria. Formulations containing ampicillin have been used to treat a variety of bacterial infections. This is a β-lactam antibiotic that inhibits bacterial cell-wall synthesis by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Administration with β-lactamase cleaves the β-lactam ring of Ampicillin and inactivates it. Ampicillin is widely used in cell culture as a selective agent for transformed cells expressing β-lactamase. Can also be used as reference material.
(1) E. Lockey, et al.; Br. J. Clin. Pract. 16, 13 (1962) | (2) H.J. Rogers & J. Mandelstam; Biochem. J. 84, 299 (1962) | (3) D.M. Campoli-Richards & R.N. Brogden; Drugs 33, 577 (1987) (Review) | (4) P.I. Rafailidis, et al.; Drugs 67, 1829 (2007) (Review) | (5) E.G. Awji, et al.; J. Vet. Med. Sci. 74, 1091 (2012)