|Synonyms||O-(Methylcarbamoyl)-2-methyl-2-(methylthio)propionaldehyd-oxime; NSC 379586; UC-21149; Temik|
|Purity Chemicals||≥99% (HPLC)|
|Appearance||Off-white to yellow solid.|
|Solubility||Soluble in water (6mg/ml) or most organic solvents.|
|Identity||Determined by NMR.|
|Declaration||Manufactured by Chemodex.|
|Other Product Data||
Click here for Original Manufacturer Product Datasheet
|Shipping and Handling|
|Short Term Storage||+4°C|
|Long Term Storage||-20°C|
Keep cool and dry.
Protect from light and moisture.
|Use/Stability||Stable for at least 2 years after receipt when stored at -20°C.|
|Product Specification Sheet|
Carbamate pesticide that reversibly inhibits acetylcholinesterase, causing rapid accumulation of acetylcholine at the synaptic cleft. Used as a pesticide and as fast-acting acetylcholinesterase inhibitor for research purposes to study cholinergic neurotransmission in simple systems such as the nematode C. elegans. It is the active ingredient in mixtures used to control insect, mite, and nematode pests in agriculture. Aldicarb has a high acute mammalian toxicity (LD50 = 0.3-0.5 mg/kg) following oral or parenteral administration. Compound can be used as analytical reference material.
(1) J.F. Risher, et al.; Environ. Health Perspect. 72, 267 (1987) | (2) M.G. Cid & E. Matos; Mutat. Res. 191, 99 (1987) | (3) P. Thomas, et al.; Fundam. Appl. Toxicol. 15, 221 (1990) | (4) R.L. Baron; Environ. Health Perspect. 102, 23 (1994) | (5) E. Maran, et al.; Food Chem. Toxicol. 48, 1592 (2010) | (6) S. Suo, & S. Ishiura; PLoS One 8, e72578 (2013) | (7) R.V. Shamagsumova, et al.; Talanta 144, 559 (2015)
- Chronic temperature stress inhibits reproduction and disrupts endocytosis via chaperone titration in Caenorhabditis elegans: R.N. Plagens, et al.; BMC Biol. 19, 75 (2021)