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Chemodex
Andrographolide
108
CHF
CHF 108.00
In stock
CDX-A0576-M500500 mgCHF 108.00
| Product Details | |
|---|---|
| Synonyms | Andrographis |
| Product Type | Chemical |
| Properties | |
| Formula |
C20H30O5 |
| MW | 350.455 |
| CAS | 5508-58-7 |
| RTECS | LU3490750 |
| Source/Host Chemicals | Plant |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | White to light yellow powder. |
| Solubility | Soluble in chloroform, DMF (15mg/ml) or DMSO (2mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | BOJKULTULYSRAS-OTESTREVSA-N |
| Smiles | C=C1CC[C@@]([C@@](CO)(C)[C@H](O)CC2)([H])[C@]2(C)[C@@H]1C/C=C3C(OC[C@H]/3O)=O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | -20°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Andrographolide, a bioactive diterpene lactone, is the main constituent of Andrographis paniculata, a plant used in traditional medicines. It is known to have different biological properties such as anti-inflammatory, immunosuppressive, antidiabetic, antihyperglycemic, antibacterial, antioxidant, antinoniceptive, antimalarial, anticancer and hepatoprotective activity. It also shows potent anti-viral effect against dengue virus. It blocks T-cell proliferation and the proliferation of several cancer cell lines in vitro. It acts as an irreversible antagonist of NF-κ and AP-1 (IC50 ≤ 15 µM) activation, and prevents in vitro and in vivo T cell activation.
Product References
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