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Chemodex
N-Aminofluorescein
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CHF
CHF 161.00
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CDX-A0936-M05050 mgCHF 161.00
CDX-A0936-M100100 mgCHF 258.00
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Product Details | |
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Synonyms | 2-Amino-3',6'-dihydroxyspiro[isoindole-3,9'-xanthene]-1-one; 2-Amino-3',6'-dihydroxyspiro[isoindoline-1,9'-xanthen]-3-one; NSC 374134 |
Product Type | Chemical |
Properties | |
Formula | C20H14N2O4 |
MW | 346.34 |
CAS | 98907-26-7 |
Source/Host Chemicals | Synthetic |
Purity Chemicals | ≥98% |
Appearance | Off white to slight yellow powder. |
Solubility | Soluble in DMSO (50mg/ml). |
Identity | Determined by 1H-NMR. |
Declaration | Manufactured by Chemodex. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | CHYVTSCIBXXQJT-UHFFFAOYSA-N |
Smiles | O=C(C1=C2C=CC=C1)N(N)C32C4=CC=C(O)C=C4OC5=C3C=CC(O)=C5 |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +20°C |
Long Term Storage | +4°C |
Handling Advice | Protect from light and moisture. |
Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
Documents | |
Product Specification Sheet | |
Datasheet |
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Description
N-Aminofluorescein is a fluorescein hydrazide with spiro ring structure and described as a highly selective and sensitive fluorescence probe for Cu2+. It absorbs maximally around 490-495 nm and emits bright green fluorescence near 515-520 nm, with a high quantum yield. It can be used for direct detection of Cu2+ in biological systems. Spectral Data: λex/em = 495/516nm. The presence of the exocyclic amino group in the structure, allows for selective chemical reactivity, making it suitable for use as a building block in the design of redox-sensitive probes, labeling reagents, and diagnostic sensors.
Product References
(1) M. Adamczyk & J. Grote; Tetrahedr. Lett. 41, 807 (2000) | (2) X.-F. Yang, et al.; Microchim. Acta 149, 123 (2005) | (3) X. Chen & H. Ma; Anal. Chim. Acta 575, 217 (2006) | (4) X.-F. Yang, et al.; Anal. Chim. Acta 584, 95 (2007) | (5) T. Li, et al.; Dyes Pigm. 88, 103 (2011) | (6) C. Shen, et al.; Chem. Commun. 51, 6312 (2015) | (7) C. Cetintas, et al.; Sens. Actuat. B: Chem. 234, 109 (2016) | (8) Y.L. Chen, et al.; J. Luminescence 275, 120747 (2024) | (9) H.T. Zhi, et al.; Bioorg. Chem. 147, 107421 (2024)