Sulfo-NHS-LC-Biotin . Na

CHF 48.00
In stock
CDX-B0310-M01010 mgCHF 48.00
CDX-B0310-M05050 mgCHF 177.00
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Product Details
Synonyms EZ-Link Sulfo-NHS-LC-Biotin; Sulfosuccinimidyl 6-(biotinamido)hexanoate; Biotinamidohexanoic acid 3-sulfo-N-hydroxysuccinimide ester sodium salt
Product Type Chemical


MW 556.59
CAS 191671-46-2 | 127062-22-0
Source/Host Chemicals Synthetic.
Purity Chemicals ≥90% (NMR)
Appearance White to off-white powder.
Solubility Soluble in water (10mg/ml), DMSO or DMF.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Smiles O=C(NCCCCCC(ON1C(CC(S(=O)([O-])=O)C1=O)=O)=O)CCCC[C@@H]2SC[C@@]3([H])[C@]2([H])NC(N3)=O.[Na+]
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

Sulfo-NHS-LC-Biotin is an amino-reactive biotinylation reagent with a long spacer arm. The 6-aminocaproic acid spacer arm provides distance between the biotin and the target ligand which helps alleviate steric hindrance, in addition it forms permanent amide bonds. The sodium sulfonate groups render this compound water-soluble and prevent it from crossing the lipid bi-layer of the cell membrane, making it a tool to label cell surface proteins. In addition, Sulfo-NHS-LC-Biotin is used to biotinylate antibodies, proteins, peptides, or amino acids by reacting with primary amines as found in the N-terminus and Lysine side chains. Optimal reaction conditions are at a pH of 7-9. Avoid amine-containing buffers, which may compete in the acylation reaction.

Product References

(1) G.T. Hermanson; Bioconjugate Techn. 2nd p506-545 (2008)

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