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Chemodex
18-Crownether-6
54
CHF
CHF 54.00
In stock
CDX-C0143-G01010 gCHF 54.00
CDX-C0143-G05050 gCHF 189.00
| Product Details | |
|---|---|
| Synonyms | 18-Crown-6; 1,4,7,10,13,16-Hexaoxacyclooctadecane |
| Product Type | Chemical |
| Properties | |
| Formula |
C12H24O6 |
| MW | 264.32 |
| CAS | 17455-13-9 |
| RTECS | MP4500000 |
| Purity Chemicals | ≥99% (HPLC) |
| Appearance | Light yellow powder. |
| Solubility | Soluble in chloroform (50 mg/ml), methanol, ethanol, benzene or water. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | XEZNGIUYQVAUSS-UHFFFAOYSA-N |
| Smiles | C1OCCOCCOCCOCCOCCOC1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at RT. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
18-Crownether-6 (18-crown-6) is ionophoric and used as an efficient phase transfer catalyst and as a complexing agent with a variety of small cations. It is involved in the synthesis of diaryl ethers, diaryl thioethers and diarylamines mediated by potassium fluoride-alumina and 18-crown-6. Used to solubilizing simple metal salts in nonpolar and dipolar aprotic solvents where solvation of the anionic portion of the salt should be minimal. It facilitates the solubility of potassium permanganate in benzene, which is used for oxidizing the organic compounds. It is used to accelerate various substitution reactions as well as enhances the power of nucleophiles such as potassium acetate. It is utilized in the alkylation reactions in the presence of potassium carbonate, N-alkylation of glutarimide and succinimide with dimethylcarbonate. The complex formed by its reaction with potassium cyanide acts as a catalyst in the cyanosilylation of aldehydes, ketones and quinines with trimethylsilyl cyanide (TMSCN).
Product References
(1) P. Solovev, et al.; J. Org. Chem. 61, 5221 (1996) | (2) G. Rounaghi, et al.; Talanta 44, 275 (1997) | (3) J.S. Sawyer, et al.; J. Org. Chem. 63, 6338 (1998) | (4) S. Kado & K. Kimura; JACS 125, 4560 (2003) | (5) D.A. Richens, et al.; J. Chromatogr A. 1016, 155 (2003) | (6) D.L. Kirschner & T.K. Green; Carbohydr. Res. 340, 1773 (2005) | (7) N. Hirayama, et al.; Anal. Sci. 24, 697 (2008) | (8) R.M. Burks & D.S. Hage; Electrophoresis 30, 657 (2009) | (9) A.G. Vendilo, et al.; Molecules 14, 5001 (2009) | (10) P. Lasitha & E. Prasad; Chemistry 22, 10558 (2016) | (11) A.K. Junker, et al.; Inorg. Chem. 55, 12299 (2016) | (12) L. Martin, et al.; Inorg. Chem. 56, 717 (2017)