CHF 108.00
In stock
CDX-C0260-M01010 mgCHF 108.00
CDX-C0260-M05050 mgCHF 434.00
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Product Details
Synonyms 1-[2-(Diethylamino)ethyl]-3-(p-methoxybenzyl)-2-quinoxalone; Spadon; Spasmium
Product Type Chemical
Formula C22H27N3O2
MW 365.47
CAS 23465-76-1
Source/Host Chemicals Synthetic.
Purity Chemicals ≥99% (HPLC)
Appearance White or slightly yellow, fine powder.
Solubility Soluble in DMSO (10 mg/ml). Insolube in water.
Identity Determined by NMR.
Declaration Manufactured by Chemodex.
Other Product Data

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Our product description may differ slightly from the original manufacturers product datasheet.

Smiles O=C1N(CCN(CC)CC)C2=C(C=CC=C2)N=C1CC3=CC=C(OC)C=C3
Shipping and Handling
Shipping AMBIENT
Short Term Storage +20°C
Long Term Storage +4°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at +4°C.
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

Quinoxaline compound, originally developed as a spasmolytic drug. Acts as an N-type calcium channel blocker, competitive AMPA receptor antagonist, and non-competitive NMDA receptor antagonist. Antioxidant agent through partial prevention of the formation and the highly active scavenging of hydroxyl radicals. Used to treat inner ear diseases such as tinnitus. Shown to inhibit tumor-promoting factors and potentially useful as a chemotherapeutic agent.

Product References

(1) Y. Ishida, et al., Br. J. Pharmacol. 71, 343 (1980) | (2) B. Saletu, et al.; Arzneimittelforsch. 45, 217 (1995) | (3) D.M. Denk, et al.; Acta Otolaryngol. 117, 825 (1997) | (4) H. Nohl, et al.; Biofactors 19, 79 (2003) | (5) G. Haymerle, et al.; Eur. Arch. Otorhinolaryngol. 272, 3451 (2015)

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