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Chemodex
3-Chloro-4-methyl-7-hydroxycoumarin
49
CHF
CHF 49.00
In stock
CDX-C0351-G0011 gCHF 49.00
CDX-C0351-G0055 gCHF 196.00
| Product Details | |
|---|---|
| Synonyms | Chlorferon; 3-Chloro-4-methylumbelliferone; 3-chloro-7-hydroxy-4-methylcoumarin; CHMC ;Chlorferone; NSC 24924; NSC 44204 |
| Product Type | Chemical |
| Properties | |
| Formula | C10H7ClO3 |
| MW | 210.61 |
| CAS | 6174-86-3 |
| Source/Host Chemicals | Synthetic |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | White to off-white powder. |
| Solubility | Soluble in ethanol. |
| Identity | Determined by NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | ODZHLDRQCZXQFQ-UHFFFAOYSA-N |
| Smiles | O=C1OC2=C(C=CC(O)=C2)C(C)=C1Cl |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | -20°C |
| Handling Advice |
Keep cool and dry. Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Major metabolite and hydrolysis product of coumaphos, an organophosphate pesticide. Shown to have acetylcholinesterase and butyrylcholinesterase inhibitor activity and moderate to weak α-glucosidase inhibitory and antioxidant scavenging activity. Also used as a building block in the synthesis of fluorogenic substrates for the detection of bacterial β-Galactosidase.
Product References
(1) V. Simeon-Rudolf, et al.; Chem. Biol. Interact. 119-120, 119 (1999) | (2) T. Jindal, et al.; J. Environ. Sci. Health B. 35, 309 (2000) | (3) K.F. Chilvers, et al.; J. Appl. Microbiol. 91, 1118 (2001) | (4) J. Ha, et al.; Bioresour. Technol. 100, 1138 (2009) | (5) B.C. Raju, et al.; Bioorg. Med. Chem. 18, 358 (2010)
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