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Chemodex
Coumarin-3-carboxylic acid
129
CHF
CHF 129.00
In stock
CDX-C0357-G02525 gCHF 129.00
| Product Details | |
|---|---|
| Synonyms | 3-CCA; 3-Carboxycoumarin; 2-Oxo-2H-1-benzopyran-3-carboxylic acid; BRN 0154276; NSC 14797; NSC 53239 |
| Product Type | Chemical |
| Properties | |
| Formula | C10H6O4 |
| MW | 190.15 |
| CAS | 531-81-7 |
| RTECS | DJ2490000 |
| Source/Host Chemicals | Synthetic. |
| Purity Chemicals | ≥98% (NMR) |
| Appearance | Beige powder. |
| Solubility | Soluble in DMSO. Slightly soluble in water (1mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | ACMLKANOGIVEPB-UHFFFAOYSA-N |
| Smiles | O=C1OC2=CC=CC=C2C=C1C(O)=O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Coumarin-3-carboxylic acid can be used for quantitative, sensitive, specific detection of hydroxyl radicals (.OH) in aqueous solutions. Spectral Data: λex=395nm; λem=450nm. Fluorescence detection of 3-CCA hydroxylation allows real-time measurement of the kinetics of .OH generation (by γ-irradiation or chemically). Coumarin-3-carboxylic acid is also a building block and intermediate for the synthesis of coumarins which are well known natural products for their diverse biological activities.
Product References
[1] Y. Manevich, et al.; Radiat. Res. 148, 580 (1997) | [2] B. Thati, et al.; Cancer Lett. 248, 321 (2007) | [3] S. Yamashita, et al.; Free Radic. Res. 46, 861 (2012) | [4] H. Ji, et al.; Bioorg. Med. Chem. 29, 115870 (2021) | [5] S.N. Esfahani, et al.; Sci. Rep. 11, 20088 (2021) | [6] Q.Yang, et al.; Photochem. Photobiol. Sci. 21, 1481 (2022)