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Chemodex
Coenzyme Q10
122
CHF
CHF 122.00
In stock
CDX-C0661-M500500 mgCHF 122.00
CDX-C0661-G0011 gCHF 197.00
| Product Details | |
|---|---|
| Synonyms | CoQ10; NSC 140865; Ubidecarenone; Ubiquinone-10; Ubiquinone Q10; Q-10; Vitamin Q |
| Product Type | Chemical |
| Properties | |
| Formula |
C59H90O4 |
| MW | 863.34 |
| CAS | 303-98-0 |
| RTECS | DK3900000 |
| Source/Host Chemicals | Synthetic |
| Purity Chemicals | ≥98% (T) |
| Appearance | Yellow to orange powder. |
| Solubility | Soluble in ethanol (1mg/ml), DMF (10mg/ml) or chloroform (20mg/ml). Insoluble in water. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | ACTIUHUUMQJHFO-UPTCCGCDSA-N |
| Smiles | O=C(C(OC)=C1OC)C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(CC/C=C(C)/CC/C=C(CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/C)\C)\C)=C(C)C1=O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Coenzyme Q10 (CoQ10) is a component of the electron transport chain of the mitochondria and participates in aerobic cellular respiration, generating energy in the form of ATP. In its reduced form, CoQ10 acts as an antioxidant, preventing the formation of reactive oxygen species and displaying neuroprotective activity. CoQ10 deficiencies have been associated with heart failure, hypertension, parkinsonism, mitochondrial encephalomyopathies and other chronic diseases. Shown to modulate the nitric oxide pathway, inhibit LDL oxidation and suppress the down regulation of NOSIII (endothelial nitric oxide synthase, eNOS) and up-regulation of NOSII (inducible nitric oxide synthase, iNOS).
Product References
(1) F.L. Crane; J. Am. Coll. Nutr. 20, 591 (2001) | (2) C.W. Shults; Curr. Med. Chem. 10, 1917 (2003) | (3) A.J. Young, et al; CNS Spectr. 12, 62 (2007) | (4) R. Saini; J. Pharm. Bioallied Sci. 3, 466 (2011) | (5) C.M. Quinzii & M. Hirano; BioFactors 37, 361 (2011) | (6) I. Bogeski, et al.; JACS 133, 9293 (2011) | (7) K.L. Tsai, et al.; J. Nutr. Biochem. 23, 458 (2012)