7-Diethylaminocoumarin-3-carboxylic acid N-succinimidyl ester

CHF 199.00
In stock
CDX-D0037-M100100 mgCHF 199.00
CDX-D0037-G0011 gCHF 1'640.00
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Product Details
Synonyms 7-DCCAE
Product Type Chemical
Properties
Formula C18H18N2O6
MW 358.35
CAS 139346-57-9
Source/Host Chemicals Synthetic.
Purity Chemicals ≥96% (HPLC)
Appearance Yellow solid.
Solubility Soluble in DMSO, DMF or acetonitrile.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key NUNPVRICKDZFLK-UHFFFAOYSA-N
Smiles CCN(CC)C1=CC2=C(C=C1)C=C(C(=O)ON1C(=O)CCC1=O)C(=O)O2
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
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Product Specification Sheet
Datasheet Download PDF

Derivatives of 7-aminocoumarins are the most extensively utilized labeling reagents for preparing brightly blue fluorescent conjugates of proteins and nucleic acid. Labeled amino acids are detected with visible semiconductor laser fluorometry using second harmonic emission (415 nm) of the near-infrared semiconductor laser. Arginine, proline, serine and glycine have been detected with detection limits around 100 amol levels. The fluorescent-labelling better matches the excitation-wavelength of standard blue lasers than conventional fluorescein-isothiocyyanate.

Product References

(1) B. Steinberg et al.; PNAS 104(22), 9523 (2007) | (2) A.K. Bhunia et al.; Chem. Biol. Chem. 8(14), 1642 (2007) | (3) T. Higashijima et al.; Anal. Chem. 64, 711 (1992)

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