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Chemodex
7-Diethylaminocoumarin-3-carboxylic acid N-succinimidyl ester
211
CHF
CHF 211.00
In stock
CDX-D0037-M100100 mgCHF 211.00
CDX-D0037-G0011 gCHF 1'744.00
| Product Details | |
|---|---|
| Synonyms | 7-DCCAE |
| Product Type | Chemical |
| Properties | |
| Formula | C18H18N2O6 |
| MW | 358.35 |
| CAS | 139346-57-9 |
| Source/Host Chemicals | Synthetic. |
| Purity Chemicals | ≥96% (HPLC) |
| Appearance | Yellow solid. |
| Solubility | Soluble in DMSO, DMF or acetonitrile. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | NUNPVRICKDZFLK-UHFFFAOYSA-N |
| Smiles | CCN(CC)C1=CC2=C(C=C1)C=C(C(=O)ON1C(=O)CCC1=O)C(=O)O2 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Derivatives of 7-aminocoumarins are the most extensively utilized labeling reagents for preparing brightly blue fluorescent conjugates of proteins and nucleic acid. Labeled amino acids are detected with visible semiconductor laser fluorometry using second harmonic emission (415 nm) of the near-infrared semiconductor laser. Arginine, proline, serine and glycine have been detected with detection limits around 100 amol levels. The fluorescent-labelling better matches the excitation-wavelength of standard blue lasers than conventional fluorescein-isothiocyyanate.
Product References
(1) B. Steinberg et al.; PNAS 104(22), 9523 (2007) | (2) A.K. Bhunia et al.; Chem. Biol. Chem. 8(14), 1642 (2007) | (3) T. Higashijima et al.; Anal. Chem. 64, 711 (1992)
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