|Purity Chemicals||≥97% (HPLC)|
|Appearance||Light yellow solid.|
|Solubility||Soluble in methanol, DMF or acetonitrile.|
|Identity||Determined by 1H-NMR.|
|Declaration||Manufactured by Chemodex.|
|Other Product Data||
Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
|Shipping and Handling|
|Short Term Storage||+4°C|
|Long Term Storage||-20°C|
|Handling Advice||Protect from light and moisture.|
|Use/Stability||Stable for at least 2 years after receipt when stored at -20°C.|
|Product Specification Sheet|
N,N-Dimethyl-6-dodecanoyl-2-naphthylamine (Laurdan) is used as an environmentally sensitive probe for the labeling of plasma membranes. The lauroyl-sidechain integrates into the hydrophobic core of biological membranes, the polar fluorescent moiety is at level of the glycerol-backbone. Dipolar relaxation processes of the naphtylamine-moiety with neighboring polar molecules lead to wavelength-shifts of the emission-spectra. The physical state of the membrane and effects of temperature, cholesterol or ethanol on various membrane-systems have been monitored.
(1) S.S. Antollini et al.; Meth. Mol. Biol. 400, 531 (2007) | (2) Y.L. Zhang et al.; Biochem. Biophys. Res. Comm. 347(3), 838 (2006) | (3) L. Bagatolli et al.; Biochimica et Biophysica Acta 1325, 80 (1997) | (4) L.I. Hellgren et al.; Plant Physiol. Biochem. 34(4), 455 (1996) | (5) G. Weber et al.; Biochemistry 18(14), 3075 (1979)