CHF 183.00
In stock
CDX-D0098-M05050 mgCHF 183.00
CDX-D0098-M250250 mgCHF 732.00
CDX-D0098-G0011 gCHF 2'510.00
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Product Details
Synonyms N,N-Dimethyl-6-dodecanoyl-2-naphthylamine
Product Type Chemical
Formula C24H35NO
MW 353.54
CAS 74515-25-6
Source/Host Chemicals Synthetic.
Purity Chemicals ≥97% (HPLC)
Appearance Light yellow solid.
Solubility Soluble in methanol, DMF or acetonitrile.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

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Our product description may differ slightly from the original manufacturers product datasheet.

Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF

N,N-Dimethyl-6-dodecanoyl-2-naphthylamine (Laurdan) is used as an environmentally sensitive probe for the labeling of plasma membranes. The lauroyl-sidechain integrates into the hydrophobic core of biological membranes, the polar fluorescent moiety is at level of the glycerol-backbone. Dipolar relaxation processes of the naphtylamine-moiety with neighboring polar molecules lead to wavelength-shifts of the emission-spectra. The physical state of the membrane and effects of temperature, cholesterol or ethanol on various membrane-systems have been monitored.

Product References

(1) S.S. Antollini et al.; Meth. Mol. Biol. 400, 531 (2007) | (2) Y.L. Zhang et al.; Biochem. Biophys. Res. Comm. 347(3), 838 (2006) | (3) L. Bagatolli et al.; Biochimica et Biophysica Acta 1325, 80 (1997) | (4) L.I. Hellgren et al.; Plant Physiol. Biochem. 34(4), 455 (1996) | (5) G. Weber et al.; Biochemistry 18(14), 3075 (1979)

Role of Negatively Charged Lipids Achieving Rapid Accumulation of Water-Soluble Molecules and Macromolecules into Cell-Sized Liposomes against a Concentration Gradient: H. Sugiyama, et al.; Langmuir ahead of print (2021)

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