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Chemodex
AGD
231
CHF
CHF 231.00
In stock
CDX-D0169-M100100 mgCHF 231.00
CDX-D0169-M250250 mgCHF 474.00
| Product Details | |
|---|---|
| Synonyms | 7-(Diethylamino)-N-(1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)-2-oxo-2H-chromene-3-carboxamide |
| Product Type | Chemical |
| Properties | |
| Formula | C18H24N2O6 |
| MW | 364.39 |
| CAS | 1456890-74-6 |
| Source/Host Chemicals | Synthetic. |
| Purity Chemicals | ≥95% (NMR) |
| Appearance | Light yellow powder. |
| Solubility | Soluble in DMSO or water. |
| Identity | Determined by NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | YGMFXQGOHXJXGN-UHFFFAOYSA-N |
| Smiles | O=C(C(C1=O)=CC2=C(O1)C=C(N(CC)CC)C=C2)NC(CO)(CO)CO |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | -20°C |
| Handling Advice |
Keep cool and dry. Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Coumarin-based 'turn-off' fluorescent probe. Highly selective for ferrous ions (Fe(2+)) and can reversibly detect them in aqueous medium. The probe localizes to the cell membrane in living cells, where it can detect changes in Fe(2+) concentration. Molecular dynamics (MD) simulations indicate that AGD interacts with the lipid bilayer at the level of the glycerol moieties. Spectral data: Excitation=430nm; Emission=480nm (HEPES, pH 7.4 at RT).
Product References
(1) O. Garcia-Beltran, et al.; Eur. J. Med. Chem. 67, 60 (2013) | (2) M.E. Aliaga, et al.; New J. Chem. 39, 3084 (2015)