|Purity Chemicals||≥95% (NMR)|
|Appearance||Light yellow powder.|
|Solubility||Soluble in DMSO or water.|
|Identity||Determined by NMR.|
|Declaration||Manufactured by Chemodex.|
|Other Product Data||
Click here for Original Manufacturer Product Datasheet
|Shipping and Handling|
|Short Term Storage||+20°C|
|Long Term Storage||-20°C|
Keep cool and dry.
Protect from light and moisture.
|Use/Stability||Stable for at least 2 years after receipt when stored at -20°C.|
|Product Specification Sheet|
Coumarin-based 'turn-off' fluorescent probe. Highly selective for ferrous ions (Fe(2+)) and can reversibly detect them in aqueous medium. The probe localizes to the cell membrane in living cells, where it can detect changes in Fe(2+) concentration. Molecular dynamics (MD) simulations indicate that AGD interacts with the lipid bilayer at the level of the glycerol moieties. Spectral data: Excitation=430nm; Emission=480nm (HEPES, pH 7.4 at RT).
(1) O. Garcia-Beltran, et al.; Eur. J. Med. Chem. 67, 60 (2013) | (2) M.E. Aliaga, et al.; New J. Chem. 39, 3084 (2015)