|Synonyms||N-(5-Aminopentyl)-5-dimethylaminonaphthalene-1-sulfonamide; N-(Dimethylaminonaphthalenesulfonyl)-1,5-pentanediamine; MDC; Monodansyl cadaverine|
|Purity Chemicals||≥98% (NMR)|
|Solubility||Soluble in methanol or DMSO.|
|Declaration||Manufactured by Chemodex.|
|Other Product Data||
Click here for Original Manufacturer Product Datasheet
|Shipping and Handling|
|Short Term Storage||-20°C|
|Long Term Storage||-20°C|
Keep cool and dry.
Protect from light and moisture.
|Use/Stability||Stable for at least 2 years after receipt when stored at -20°C.|
|Product Specification Sheet|
Fluorescent probe for derivatization of aldehydes, ketones and carboxylic acids. Used to prepare small fluorescent biomolecules via amidation or reductive amination. Used to monitor autophagy. Functions by marking the autophagosomes, which allows researchers to follow the molecular components of the process throughout. Accumulates in autophagic vacuoles due to a combination of ion trapping and specific interactions with membrane lipids. Has biological applications in measuring cardiac autophagic flux, studying Parkinson's disease, peritoneal ovarian tumor dissemination and respiratory diseases. This fluorescent tag is preferred over other due to its specificity and simplicity in detecting autophagic vesicles. Fluorescent substrate for assaying transamidating enzymes. Shown to inhibit endocytosis, the fibrin-stabilizing factor and epidermal growth factor (EGF) internalization. Dansyl dyes have environmentally sensitive fluorescence quantum yields and emission maxima along with large stokes shifts. Spectral Data: λex 335nm; λem518 nm in methanol.
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