Chemodex

1,1'-Dibutyl-3,3,3',3'-tetramethyl indocarbocyanine iodide

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Product Details
Synonyms DiIC4(3)
Product Type Chemical
Properties
Formula C31H41N2 . I
MW 568.58
CAS 132752-00-2
Source/Host Chemicals Synthetic
Purity Chemicals ≥98% (HPLC)
Appearance Violett crystalline solid.
Solubility Soluble in DMSO or methanol.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

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Our product description may differ slightly from the original manufacturer's product datasheet.

InChi Key CVTQMCMIKOZBTI-UHFFFAOYSA-M
Smiles CCCCN\1C2=CC=CC=C2C(/C1=C\C=C\C3=[N+](C4=CC=CC=C4C3(C)C)CCCC)(C)C.[I-]
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep under inert gas.
Protect from light and oxygen.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
Product Specification Sheet
Datasheet Download PDF
Description
DiIC4(3) is a fluorescent carbocyanine dye with butyl chains widely used for membrane staining due to its hydrophobic nature, which helps it intercalate well into lipid bilayers. Carbocyanine dyes are unique organic molecules that contain a conjugated electron-deficient system between two heterocyclic nitrogen atoms that provides characteristically long absorption and emission wavelengths. It can be used for cell tracking as it is stably retained in membranes and in fixed tissue slices for anterograde and retrograde tracing. Spectral Data: Excitation max: ~550-555nm, Emission max: ~565-570nm (accord. Lit). Also used as intermediate for the synthesis of selective protein arginine methyltransferases (PRMT) inhibitors. Intermediate for the synthesis of fluorescent probes.
Product References
(1) G. Suaerwein & G.B. Schuster; J. Phys. Chem. 95, 1903 (1991) | (2) G. Beckford, et al.; Talanta 92, 45 (2012) | (3) S.H. Sinha, et al.; Eur. J. Med. Chem. 54, 647 (2012) | (4) H. Hu, et al.; J. Med. Chem. 58, 1228 (2015) | (5) M. Matsui, et al.; Tetrahedron 71, 3528 (2015)
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