CHF 135.00
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CDX-D0318-G0011 gCHF 135.00
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Product Details
Product Type Chemical
Formula C7H9N5
MW 163.18
CAS 938-55-6
Source/Host Chemicals Synthetic.
Purity Chemicals ≥97% (HPLC)
Appearance White solid.
Solubility Soluble in DMF.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

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Smiles CN(C)C1=C2NC=NC2=NC=N1
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at +4°C.
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Product Specification Sheet
Datasheet Download PDF

A puromycin analog that acts as a protein kinase inhibitor. Selectively induces premature mitosis in mammalian cells. Inhibits TNF-α upregulation of ICAM-1, lipolysis, and the activation of JNK/SAPK. Inhibits p34cdc2/cyclin B (IC50 = 300 µM). Induces apoptosis in S-phase-arrested HeLa cells (~5 mM).

Product References

(1) H. Bredereck et al.; Berichte der Deutschen Chemischen Gesellschaft 73B, 1058-65 (1940) | (2) J. Vesely et al.; European Journal of Biochemistry 224(2), 771-86 (1994) | (3) P. Chesne et al.; Nature Biotechnology 20(4), 366-369 (2002)

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